2-Chlorobenzamide
- CAS NO.:609-66-5
- Empirical Formula: C7H6ClNO
- Molecular Weight: 155.58
- MDL number: MFCD00007973
- EINECS: 210-195-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:45:42
What is 2-Chlorobenzamide?
Chemical properties
The substance is an almost white crystalline powder that can be dissolved in solvents such as benzene and toluene.
The Uses of 2-Chlorobenzamide
2-Chlorobenzamide is used to synthesize chlortetracycline and o-chlorobenzoyl isocyanate, which is an intermediate in chlortetracycline synthesis.
General Description
2-Chlorobenzamide is the major degradation product of CCU (1-(2-chlorobenzoyl)-3-(4-chlorophenyl) urea), a new insect growth regulator. It undergoes room temperature Pd-mediated hydrodehalogenations with KF and polymethylhydrosiloxane (PMHS) to yield benzamide. t undergoes reduction with NaBH4 in diglyme at 162°C to yield 2-chlorobenzonitrile.
Synthesis
Prepared by reacting o-chlorobenzoyl chloride with ammonia.
Properties of 2-Chlorobenzamide
| Melting point: | 142-144 °C(lit.) |
| Boiling point: | 275.0±23.0 °C(Predicted) |
| Density | 1.2187 (rough estimate) |
| refractive index | 1.5618 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 15.36±0.50(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 508510 |
| CAS DataBase Reference | 609-66-5(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Chlorobenzamide (609-66-5) |
Safety information for 2-Chlorobenzamide
| Signal word | Warning |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H330:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P320:Specific treatment is urgent (see … on this label). P330:Rinse mouth. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Chlorobenzamide
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