2-Amino-p-cresol
Synonym(s):2-Amino-p-cresol;2-Hydroxy-5-methylaniline;3-Amino-4-hydroxytoluene
- CAS NO.：95-84-1
- Empirical Formula: C7H9NO
- Molecular Weight: 123.15
- MDL number: MFCD00007699
- EINECS: 202-457-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-27 08:46:37
What is 2-Amino-p-cresol?
Chemical properties
White crystal powder
The Uses of 2-Amino-p-cresol
2-Amino-4-methylphenol was used in the synthesis of novel functionalized spiropyran derivatives of 2H-1,3-benzoxazinone series.
General Description
Brown powder.
Air & Water Reactions
2-Amino-p-cresol may be sensitive to prolonged exposure to air. Insoluble in water.
Reactivity Profile
2-Amino-p-cresol reacts with strong oxidizing agents.
Fire Hazard
Flash point data for 2-Amino-p-cresol are not available, however 2-Amino-p-cresol is probably combustible.
Purification Methods
Recrystallise the cresol from H2O, Et2O or toluene. It sublimes in vacuo as plates or needles. The hydrochloride has m 222-224o (dec, from aqueous EtOH). [Beilstein 13 H 601, 13 I 227, 13 II 338, 13 III 1576.]
Properties of 2-Amino-p-cresol
| Melting point: | 133-136 °C(lit.) |
| Boiling point: | 229.26°C (rough estimate) |
| Density | 1.0877 (rough estimate) |
| refractive index | 1.5706 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | slightly soluble |
| pka | 10.06±0.18(Predicted) |
| form | Flakes or Crystalline Powder |
| color | Beige to gray-brown |
| Water Solubility | slightly soluble |
| BRN | 606494 |
| CAS DataBase Reference | 95-84-1(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Amino-p-cresol (95-84-1) |
Safety information for 2-Amino-p-cresol
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Amino-p-cresol
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