2-Amino-5-chlorobenzoic acid
Synonym(s):5-Chloroanthranilic acid
- CAS NO.：635-21-2
- Empirical Formula: C7H6ClNO2
- Molecular Weight: 171.58
- MDL number: MFCD00007838
- EINECS: 211-230-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:02
What is 2-Amino-5-chlorobenzoic acid?
Chemical properties
White to light yellow crystal powder
The Uses of 2-Amino-5-chlorobenzoic acid
2-Amino-5-chlorobenzoic acid is used in the preparation of disease-modifying antirheumatic drugs (DMARDs). Also used to produce 6-chloro-3H-quinazolin-4-one at temperature of 180°C.
The Uses of 2-Amino-5-chlorobenzoic acid
2-Amino-5-chlorobenzoic acid is a chlorinated derivative of antharilic acid,it is a metabolite of the pesticide Chlordimeform and it is used in the preparation of disease-modifying antirheumatic drugs (DMARDs).
The Uses of 2-Amino-5-chlorobenzoic acid
5-Chloroanthranilic Acid is a chlorinated derivative of anthranilic acid. 5-Chloroanthranilic Acid is a metabolite of the pesticide Chlordimeform. 5-Chloroanthranilic Acid is used in the preparation o f disease-modifying antirheumatic drugs (DMARDs).
Definition
ChEBI: 2-amino-5-chlorobenzoic acid is a member of the class of chlorobenzoic acids that is benzoic acid in which the ring hydrogens at positions 2 and 5 are replaced by amino and chloro groups, respectively. It is an aminobenzoic acid, a member of monochlorobenzenes and a chlorobenzoic acid.
Properties of 2-Amino-5-chlorobenzoic acid
| Melting point: | 204-206 °C (dec.) (lit.) |
| Boiling point: | 250°C (rough estimate) |
| Density | 1.3246 (rough estimate) |
| refractive index | 1.5560 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.57±0.10(Predicted) |
| color | White to Pale Grey |
| Water Solubility | Soluble in water. |
| BRN | 639027 |
| CAS DataBase Reference | 635-21-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 2-amino-5-chloro-(635-21-2) |
| EPA Substance Registry System | Benzoic acid, 2-amino-5-chloro- (635-21-2) |
Safety information for 2-Amino-5-chlorobenzoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-5-chlorobenzoic acid
| InChIKey | IFXKXCLVKQVVDI-UHFFFAOYSA-N |
2-Amino-5-chlorobenzoic acid manufacturer
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product: 2-Amino-5-chlorobenzoic acid 635-21-2 98%
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