2-Amino-5-bromopyridine
- CAS NO.:1072-97-5
- Empirical Formula: C5H5BrN2
- Molecular Weight: 173.01
- MDL number: MFCD00006323
- EINECS: 214-019-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-28 17:38:58
What is 2-Amino-5-bromopyridine?
Chemical properties
Light yellow Cryst
The Uses of 2-Amino-5-bromopyridine
2-Amino-5-bromopyridine is used for the synthesis of polycyclic azaarenes.
What are the applications of Application
2-Amino-5-bromopyridine is available:
(1) Spectroscopic studies, vibrational spectroscopy, coordination and ortho analysis of 2-Amino-5-bromopyridine.
(2) As an organic synthesis reagent for the preparation of β-d-glucopyranosamine, β-d-galactopyranosamine compounds and polycyclic azulene compounds.
(3) The electrochemical reduction behaviour of 2-amino-5-bromopyridine in BMIMBF4 was investigated by cyclic voltammetry, and the reduction peak was -1.6 V (for Ag). Under the optimised conditions, 6-aminonicotinic acid was obtained in 75% yield and 100% selectivity. In addition, the ionic liquid was successfully recovered.
General Description
2-Amino-5-bromopyridine is a brominated aromatic amine reagent and is used for labeling of model reducing-end oligosaccharides via reductive amination.
Properties of 2-Amino-5-bromopyridine
| Melting point: | 133-138 °C (lit.) |
| Boiling point: | 230.9±20.0 °C(Predicted) |
| Density | 1.6065 (rough estimate) |
| refractive index | 1.5182 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Crystalline Powder |
| pka | 4.65±0.13(Predicted) |
| color | White to beige |
| Water Solubility | Soluble in methanol, chloroform, ethyl acetate. Slightly soluble in water. |
| BRN | 108737 |
| InChI | InChI=1S/C5H5BrN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8) |
| CAS DataBase Reference | 1072-97-5(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Amino-5-bromopyridine (1072-97-5) |
Safety information for 2-Amino-5-bromopyridine
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-5-bromopyridine
| InChIKey | WGOLHUGPTDEKCF-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C(Br)C=C1 |
2-Amino-5-bromopyridine manufacturer
BTC pharm India
JSK Chemicals
NSR Amino Organics
Lorven Biologics Pvt Ltd
SAKEM LLP
ASM Organics
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