2-Amino-4-phenylthiazole
- CAS NO.：2010-06-2
- Empirical Formula: C9H8N2S
- Molecular Weight: 176.24
- MDL number: MFCD00039680
- EINECS: 217-926-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:57
What is 2-Amino-4-phenylthiazole?
Description
2-
The Uses of 2-Amino-4-phenylthiazole
4-Phenyl-2-thiazolamine was used to prepare suberoylanilide hydroxamic acid (SAHA) analogs with cancer cell growth inhibitory activities. It was also used to synthesize ketone histone deacetylase inhibitors with antitumor activity in vivo.
What are the applications of Application
2-Amino-4-phenylthiazole is used to synthesize ketone histone deacetylase inhibitors with antitumor activity
Properties of 2-Amino-4-phenylthiazole
| Melting point: | 149-153 °C (lit.) |
| Boiling point: | 363.4±11.0 °C(Predicted) |
| Density | 1.261±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml |
| pka | 4.33±0.10(Predicted) |
| form | Crystalline Solid |
| color | White to yellow to pale orange |
| λmax | 284nm(EtOH)(lit.) |
| BRN | 128609 |
| CAS DataBase Reference | 2010-06-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Thiazolamine, 4-phenyl-(2010-06-2) |
Safety information for 2-Amino-4-phenylthiazole
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see … on this label). P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Amino-4-phenylthiazole
| InChIKey | PYSJLPAOBIGQPK-UHFFFAOYSA-N |
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