2-Amino-4-chloro-5-nitrophenol
- CAS NO.：6358-07-2
- Empirical Formula: C6H5ClN2O3
- Molecular Weight: 188.57
- MDL number: MFCD00010300
- EINECS: 228-760-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:27:40
What is 2-Amino-4-chloro-5-nitrophenol?
Chemical properties
orange powder
What are the applications of Application
2-Amino-4-chloro-5-nitrophenol is used in the synthesis of achiral analogs of duocarmycin SA (DUMSA)
General Description
Orange powder that turns dark at 392°F.
Air & Water Reactions
May be sensitive to prolonged exposure to air. Insoluble in water.
Reactivity Profile
2-Amino-4-chloro-5-nitrophenol may react with strong oxidizing agents.
Fire Hazard
Flash point data for 2-Amino-4-chloro-5-nitrophenol are not available. 2-Amino-4-chloro-5-nitrophenol is probably combustible.
Properties of 2-Amino-4-chloro-5-nitrophenol
| Melting point: | 225 °C(lit.) |
| Boiling point: | 402.4±45.0 °C(Predicted) |
| Density | 1.655±0.06 g/cm3(Predicted) |
| form | powder to crystal |
| pka | 7.45±0.24(Predicted) |
| color | Light yellow to Brown |
| Water Solubility | <0.01 g/100 mL at 22 ºC |
| Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. |
| CAS DataBase Reference | 6358-07-2(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Amino-4-chloro-5-nitrophenol (6358-07-2) |
Safety information for 2-Amino-4-chloro-5-nitrophenol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2-Amino-4-chloro-5-nitrophenol
2-Amino-4-chloro-5-nitrophenol manufacturer
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