2-Amino-3-picoline
Synonym(s):2-Amino-3-picoline
- CAS NO.：1603-40-3
- Empirical Formula: C6H8N2
- Molecular Weight: 108.14
- MDL number: MFCD00006320
- EINECS: 216-501-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:32:52
What is 2-Amino-3-picoline?
Chemical properties
2-Amino-3-picoline is CLEAR YELLOW LIQUID AFTER MELTING
The Uses of 2-Amino-3-picoline
2-Amino-3-picoline is used in the synthesis of ketones from aldehydes.
Synthesis Reference(s)
Journal of the American Chemical Society, 95, p. 4453, 1973 DOI: 10.1021/ja00794a070
Hazard
Toxic by ingestion.
Purification Methods
Recrystallise the picoline three times from *benzene, most of the residual *benzene being removed from the crystals by standing over paraffin wax chips in an evacuated desiccator. The amine is also transferred to a separating funnel under N2, and left in contact with NaOH pellets for 3hours with occasional shaking. It is then placed in a vacuum distilling flask where it is refluxed gently in a stream of dry N2 before fractionally distilling it. [Mod et al. J Phys Chem 60 1651 1956, Beilstein 22/9 V 212].
Properties of 2-Amino-3-picoline
| Melting point: | 29-31 °C (lit.) |
| Boiling point: | 221-222 °C (lit.) |
| Density | 1.073 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 233 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 1000g/l |
| form | Liquid After Melting |
| pka | pK1: 7.24(+1) (25°C) |
| color | Clear yellow |
| Water Solubility | SOLUBLE |
| Sensitive | Hygroscopic |
| BRN | 107892 |
| CAS DataBase Reference | 1603-40-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyridinamine, 3-methyl-(1603-40-3) |
| EPA Substance Registry System | 2-Pyridinamine, 3-methyl- (1603-40-3) |
Safety information for 2-Amino-3-picoline
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. |
Computed Descriptors for 2-Amino-3-picoline
| InChIKey | RGDQRXPEZUNWHX-UHFFFAOYSA-N |
2-Amino-3-picoline manufacturer
Ina pharmaceuticals Pvt Ltd
4Y
Phone:+91-7815933367
Whatsapp: +91-78159 33367
product: 2-Amino-3-Methylpyridine 1603-40-3 99%
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