2-Amino-3-methoxybenzoic acid
Synonym(s):3-Methoxyanthranilic acid
- CAS NO.：3177-80-8
- Empirical Formula: C8H9NO3
- Molecular Weight: 167.16
- MDL number: MFCD00075178
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:55:05
What is 2-Amino-3-methoxybenzoic acid?
Chemical properties
White to light brown crystals or powder
The Uses of 2-Amino-3-methoxybenzoic acid
2-Amino-3-methoxybenzoic Acid is used in the preparation of CDK1/cyclin B inhibitors for application towards antitumor treatment. In addition, it is used in the synthesis of Alogliptin, an inhibitor o f dipeptidy peptidase, which aids in the lowering of blood-glucose for potential treatment of diabetes.
Definition
ChEBI: 3-methoxyanthranilic acid is an aminobenzoic acid that is anthranilic acid in which the hydrogen at position 3 is substituted by a methoxy group. It is a metabolite of kynurenine. It has a role as a mammalian metabolite. It is a member of benzoic acids and an aminobenzoic acid. It is functionally related to an anthranilic acid. It is a conjugate acid of a 3-methoxyanthranilate.
Synthesis Reference(s)
The Journal of Organic Chemistry, 63, p. 6797, 1998 DOI: 10.1021/jo972158g
Properties of 2-Amino-3-methoxybenzoic acid
| Melting point: | 169-170 °C (lit.) |
| Boiling point: | 333.9±27.0 °C(Predicted) |
| Density | 1.303±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 4.82±0.10(Predicted) |
| color | White to yellow to brown |
| CAS DataBase Reference | 3177-80-8(CAS DataBase Reference) |
Safety information for 2-Amino-3-methoxybenzoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Amino-3-methoxybenzoic acid
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