2-Amino-1-bromonaphthalene

CAS NO.：20191-75-7
Empirical Formula: C10H8BrN
Molecular Weight: 222.08
MDL number: MFCD00086888
EINECS: 202-080-4
SAFETY DATA SHEET (SDS)
Update Date: 2025-07-16 09:55:31

What is 2-Amino-1-bromonaphthalene ?

Chemical properties

White to Light yellow to Light red powder to crystal

Synthesis

The crude naphthalen-2-amine HCl salt (790 mg, 5.5 mmol) and TsOH (170 mg, 1.1 mmol) in THF (50 mL) cooled to 0 0C were treated with NBS (982 mg, 5.5 mmol) in THF (30 mL), and the solution was allowed to warm to 23 0C. After stirring for 5 hours, the reaction mixture was washed with saturated aqueous NaHCO3 (30 mL x 2). The organic layer was dried over anhydrous sodium sulfate and was concentrated to afford 2-Amino-1-bromonaphthalene.

Properties of 2-Amino-1-bromonaphthalene

Melting point:	63-64 °C(Solv: ligroine (8032-32-4))
Boiling point:	345.5±15.0 °C(Predicted)
Density	1.563±0.06 g/cm3(Predicted)
pka	1.51±0.10(Predicted)

Safety information for 2-Amino-1-bromonaphthalene

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P330:Rinse mouth. P362:Take off contaminated clothing and wash before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…