2-Acetamido-5-nitrothiazole
- CAS NO.：140-40-9
- Empirical Formula: C5H5N3O3S
- Molecular Weight: 187.18
- MDL number: MFCD00022438
- EINECS: 205-414-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:28
What is 2-Acetamido-5-nitrothiazole?
Chemical properties
Yellow-brown solid
The Uses of 2-Acetamido-5-nitrothiazole
antiinflammatory, glucocorticoid
The Uses of 2-Acetamido-5-nitrothiazole
Nithiamide is a drug for chemotherapy. A protistocide drug with antibacterial activity.
Definition
ChEBI: Aminitrozole is an aromatic amide and a member of acetamides.
Safety Profile
Poison by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of SO, and NOx,.
Purification Methods
Recrystallise acinitrazole from EtOH or AcOH. [Hurd & Wehrmeister J Am Chem Soc 71 4007 1949, Beilstein 27 III/IV 4676.]
Properties of 2-Acetamido-5-nitrothiazole
| Melting point: | 263°C (dec.) |
| Density | 1.546 (estimate) |
| refractive index | 1.6560 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMF:3.0(Max Conc. mg/mL);16.03(Max Conc. mM) DMSO:10.0(Max Conc. mg/mL);53.43(Max Conc. mM) |
| pka | 8.78±0.50(Predicted) |
| form | solid |
| color | White to Amber |
| Merck | 14,410 |
| BRN | 167361 |
| CAS DataBase Reference | 140-40-9(CAS DataBase Reference) |
Safety information for 2-Acetamido-5-nitrothiazole
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H228:Flammable solids H301:Acute toxicity,oral H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see … on this label). P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Acetamido-5-nitrothiazole
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