2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester

CAS NO.：87414-44-6
Empirical Formula: C19H16O7
Molecular Weight: 356.33
MDL number: MFCD09752715
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-24 14:59:02

What is 2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester?

Description

Butyrolactone II is a butenolide fungal metabolite that has been found in A. terreus. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS free radicals (EC₅₀s = 11.5 and 68.5 μM, respectively). It inhibits 5-lipoxygenase (5-LO; IC₅₀ = 21.43 μg/ml) and α-glucosidase (IC₅₀ = 0.126 mM).

The Uses of 2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester

Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity.

What are the applications of Application

Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity

Storage

+4°C

Properties of 2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester

Melting point:	91-94 °C
Boiling point:	640.5±55.0 °C(Predicted)
Density	1.497±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Amorphous.
pka	8.61±0.40(Predicted)
color	White to off-white

Safety information for 2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester

Computed Descriptors for 2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester

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