2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Synonym(s):[2-(2,6-Dichloro-4-hydroxy-phenylamino)phenyl]acetic acid;4′-Hydroxy Diclofenac
- CAS NO.：64118-84-9
- Empirical Formula: C14H11Cl2NO3
- Molecular Weight: 312.15
- MDL number: MFCD01671980
- EINECS: 626-698-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
![2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Structural](https://img.chemicalbook.in/CAS/GIF/64118-84-9.gif)
What is 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID?
Description
4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE2 synthesis, it demonstrates anti-inflammatory and analgesic properties.
Chemical properties
Light Violet Solid
The Uses of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor
The Uses of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.
The Uses of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac
What are the applications of Application
4′-Hydroxy Diclofenac is a Cox-2 inhibitor and an active CYP2C9 metabolite of the NSAID diclofenac.
Definition
ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.
General Description
4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.
Properties of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
| Melting point: | 178-185°C dec. |
| Boiling point: | 432.7±45.0 °C(Predicted) |
| Density | 1.520±0.06 g/cm3(Predicted) |
| Flash point: | 2℃ |
| storage temp. | -20°C |
| solubility | Soluble in DMSO, ethanol or methanol |
| form | neat |
| pka | 4.17±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| BRN | 4198042 |
| Stability: | Light Sensitive |
Safety information for 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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