2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
Synonym(s):O-(1,2-Dihydro-2-oxo-1-pyridyl)-N,N,N′-N′-tetramethyluronium tetrafluoroborate;TPTU
- CAS NO.：125700-71-2
- Empirical Formula: C10H16N3O2.BF4
- Molecular Weight: 297.06
- MDL number: MFCD00075475
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:27:00
What is 2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate?
Chemical properties
white crystalline powder
The Uses of 2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
Coupling reagent for peptide synthesis, especially suited for segment condensation with little racemization
The Uses of 2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
Reagent for:
Amidation
Peptide Coupling
Esterification of nucleosides to solid phase supports for oligonucleoside synthesis
Properties of 2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
| Melting point: | 140 °C (dec.)(lit.) |
| storage temp. | 2-8°C |
| solubility | Soluble in water or 1% acetic acid |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | insoluble |
| Sensitive | Moisture Sensitive |
| CAS DataBase Reference | 125700-71-2(CAS DataBase Reference) |
Safety information for 2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
| InChIKey | HBQDCKPPSIWZLY-UHFFFAOYSA-M |
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