(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol

CAS NO.：1006376-60-8
Empirical Formula: C8H7ClF2O
Molecular Weight: 192.59
MDL number: MFCD09863590
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-08 10:32:36

What is (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol?

The Uses of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol

(S)-2-Chloro-1-(3,4-difluorophenyl)ethanol is a building block used in organic synthesis including bein an intermediate in the synthesis of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.

Properties of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol

Boiling point:	256.3±35.0 °C(Predicted)
Density	1.372±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	viscous liquid
pka	12.49±0.20(Predicted)
color	Clear, almost colourless

Safety information for (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H301:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.