1H-Pyrazole-1-carboxamidine hydrochloride
Synonym(s):1H-Pyrazole-1-carboxamidine hydrochloride;1-Amidinopyrazole hydrochloride;Praxadine
- CAS NO.:4023-02-3
- Empirical Formula: C4H7ClN4
- Molecular Weight: 146.58
- MDL number: MFCD00210087
- EINECS: 429-520-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:08
What is 1H-Pyrazole-1-carboxamidine hydrochloride?
Chemical properties
white to light yellow crystals or crystalline
The Uses of 1H-Pyrazole-1-carboxamidine hydrochloride
1H-Pyrazole-1-carboxamidine hydrochloride may be used in the following studies: ? Preparation of guanidylated hollow fiber membranes. ? Guanylation of amines and in peptide synthesis. ? Synthesis of bis-guanidinium-cholesterol derivatives.
The Uses of 1H-Pyrazole-1-carboxamidine hydrochloride
1H-Pyrazole-1-carboxamidine hydrochloride is a stable and versatile reagent for the efficient and chemically specific guanylation of sterically unhindered primary and secondary aliphatic amines under mild conditions. 1H-Pyrazole-1-carboxamidine hydrochloride is a useful reagent in peptide synthesis
What are the applications of Application
1H-Pyrazole-1-carboxamidine Hydrochloride is a reagent used for peptide synthesis and chemically specific guanylation of amines
General Description
1H-Pyrazole-1-carboxamidine hydrochloride, a pyrazole derivative, is a heterocyclic compound. It is widely used in drug syntheses studies. Pyrazole ring forms the main core of various nonsteroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs.
Properties of 1H-Pyrazole-1-carboxamidine hydrochloride
| Melting point: | 167-170 °C(lit.) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Crystals or Crystalline Powder |
| color | White to light yellow |
| Water Solubility | Soluble |
| BRN | 5448758 |
| CAS DataBase Reference | 4023-02-3(CAS DataBase Reference) |
Safety information for 1H-Pyrazole-1-carboxamidine hydrochloride
| Signal word | Danger |
| Pictogram(s) |
![]() Corrosion Corrosives GHS05 ![]() Exclamation Mark Irritant GHS07 ![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H373:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1H-Pyrazole-1-carboxamidine hydrochloride
1H-Pyrazole-1-carboxamidine hydrochloride manufacturer
Sainor Laboratories Pvt Ltd Unit III
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