1H-Pyrazole-1-carboxamidine hydrochloride

Synonym(s):1H-Pyrazole-1-carboxamidine hydrochloride;1-Amidinopyrazole hydrochloride;Praxadine

CAS NO.：4023-02-3
Empirical Formula: C4H7ClN4
Molecular Weight: 146.58
MDL number: MFCD00210087
EINECS: 429-520-1
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-09 10:27:52

1H-Pyrazole-1-carboxamidine hydrochloride Structural

What is 1H-Pyrazole-1-carboxamidine hydrochloride?

Chemical properties

white to light yellow crystals or crystalline

The Uses of 1H-Pyrazole-1-carboxamidine hydrochloride

1H-Pyrazole-1-carboxamidine hydrochloride is a stable and versatile reagent for the efficient and chemically specific guanylation of sterically unhindered primary and secondary aliphatic amines under mild conditions. 1H-Pyrazole-1-carboxamidine hydrochloride is a useful reagent in peptide synthesis

The Uses of 1H-Pyrazole-1-carboxamidine hydrochloride

1H-Pyrazole-1-carboxamidine hydrochloride may be used in the following studies: ? Preparation of guanidylated hollow fiber membranes. ? Guanylation of amines and in peptide synthesis. ? Synthesis of bis-guanidinium-cholesterol derivatives.

What are the applications of Application

1H-Pyrazole-1-carboxamidine Hydrochloride is a reagent used for peptide synthesis and chemically specific guanylation of amines

General Description

1H-Pyrazole-1-carboxamidine hydrochloride, a pyrazole derivative, is a heterocyclic compound. It is widely used in drug syntheses studies. Pyrazole ring forms the main core of various nonsteroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs.

Properties of 1H-Pyrazole-1-carboxamidine hydrochloride

Melting point:	167-170 °C(lit.)
storage temp.	Inert atmosphere,Room Temperature
form	Crystals or Crystalline Powder
color	White to light yellow
Water Solubility	Soluble
BRN	5448758
CAS DataBase Reference	4023-02-3(CAS DataBase Reference)

Safety information for 1H-Pyrazole-1-carboxamidine hydrochloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H373:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.