1H-Imidazole-4-carboxylic acid
- CAS NO.：1072-84-0
- Empirical Formula: C4H4N2O2
- Molecular Weight: 112.09
- MDL number: MFCD00082203
- EINECS: 214-017-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:53
What is 1H-Imidazole-4-carboxylic acid?
Chemical properties
Gray or tan powder
The Uses of 1H-Imidazole-4-carboxylic acid
4-Imidazolecarboxylic acid (ICA) was used in the synthesis of triphenymethyl-protected 4-imidazole carboxylic acid (trityl-ImCOOH) which is employed to functionalize poly(propylene imine) dendrimers.
It may be used in the following studies:
- In the synthesis of lanthanide sulfate–carboxylates, [Ln(HIMC)(SO4)(H2O)] (Ln = Dy and Eu, HIMC = 4-imidazolecarboxylic acid) by in situ decarboxylation in the presence of Cu(II) ions.
- As an internal standard to obtain calibration curve by plotting the peak area ratios of histamine (HA) and several metabolites isolated from C3H/HeNCrj mice hair relative to ICA.
- In the synthesis of tetranuclear manganese carboxylate complexes possessing imidazole-based N/O chelating ligands.
What are the applications of Application
4-Imidazolecarboxylic acid is 4-Imidazolecarboxylic acid is used in the synthesis of imidazole functionalized poly(propylene imine) dendrimers.
General Description
4-Imidazolecarboxylic acid (1H-imidazole-4-carboxylic acid, H2imc) is an imidazole derivative that contains an imidazole group and a carboxylate group. It has been widely utilized to generate different types of coordination polymers. The anion of 4-imidazolecarboxylic acid has been reported to stabilize binuclear hydroxo complexes of trivalent lanthanides in the pH range 7-10.
Properties of 1H-Imidazole-4-carboxylic acid
| Melting point: | 294-295 °C (lit.) |
| Boiling point: | 495.0±18.0 °C(Predicted) |
| Density | 1.524±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (sparingly) |
| form | Liquid |
| pka | 2.69±0.10(Predicted) |
| color | Clear colorless |
| InChI | InChI=1S/C4H4N2O2/c7-4(8)3-1-5-2-6-3/h1-2H,(H,5,6)(H,7,8) |
| CAS DataBase Reference | 1072-84-0(CAS DataBase Reference) |
Safety information for 1H-Imidazole-4-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1H-Imidazole-4-carboxylic acid
| InChIKey | NKWCGTOZTHZDHB-UHFFFAOYSA-N |
| SMILES | C1NC(C(O)=O)=CN=1 |
1H-Imidazole-4-carboxylic acid manufacturer
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 1H-Imidazole-4-carboxylic acid 1072-84-0 98%
New Products
Paroxetine Impurity G/Paroxetine Related Compound E 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) 1-aminocyclopentane carbonitrile, HCl H-D-TRP(FOR)-OH HCL 9-Mesityl-10-methylacridinium perchlorate 3-Amino-3-(4-fluorophenyl)propanoic acid Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Bisacodyl Related Compound C/Bisacodyl EP Impurity C Levothyroxine Beta Hydroxy Impurity Candesartan EP Impurity-F/Candesartan Cilexetil USP Related Compound F / Candesartan Cilexetil N2-Ethyl Impurity / 2H-N2-Ethyl Candesartan Cilexetil Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Sumatriptan Succinate USP Related Compound C N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecarboxamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide L-phenylalanine methyl ester hydrochloride 2,2'-(5-Bromomethyl-1,3-phenylene)-di(2-Methylpropionitrile) tri sodium thio phosphate L-phenylalanine, N-(pyrazinyl carbonyl) methyl ester 3-chlorobenzyl cyanide 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 4-Bromo Benzylcyanide 3-Hydroxypropionitrile valeronitrileRelated products of tetrahydrofuran
You may like
-
1H-Imidazole-4-carboxylic acid 98%View Details -
4-Imidazolecarboxylic Acid CAS 1072-84-0View Details
1072-84-0 -
Imidazole-4-carboxylic acid 95.00% CAS 1072-84-0View Details
1072-84-0 -
4-Imidazolecarboxylic acid CAS 1072-84-0View Details
1072-84-0 -
1H-Imidazole-4-carboxylic acid 1072-84-0 98%View Details
1072-84-0 -
2847776-12-7 Sumatriptan Succinate USP Related Compound C NLT 95%View Details
2847776-12-7 -
1012886-75-7(HCl Salt)/69675-10-1(Freebase) Paroxetine Impurity G/Paroxetine Related Compound E NLT 95%View Details
1012886-75-7(HCl Salt)/69675-10-1(Freebase) -
3,4 Diethoxy Benzylcyanide 99%View Details
27472-21-5
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.