1,8,9-TRIHYDROXYANTHRACENE

CAS NO.：480-22-8
Empirical Formula: C14H10O3
Molecular Weight: 226.23
MDL number: MFCD00001250
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:08:52

What is 1,8,9-TRIHYDROXYANTHRACENE?

Chemical properties

yellow crystalline powder

The Uses of 1,8,9-TRIHYDROXYANTHRACENE

Antipsoriatic.

Definition

ChEBI: An anthracenetriol that is anthracene substituted by hydroxy groups at positions 1, 8 and 9.

brand name

Anthra-Derm (Dermik); DrithoCreme (Dermik); Drithoscalp (Dermik); Lasan (Stiefel).

General Description

Odorless yellow leaflets or needles; yellow powder. Tasteless. Filtrate from water suspension is neutral to litmus. When exposed to air, alkaline solutions turn red and lose their fluorescence.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1,8,9-TRIHYDROXYANTHRACENE is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. 1,8,9-TRIHYDROXYANTHRACENE is incompatible with strong oxidizing agents. .

Fire Hazard

Flash point data for 1,8,9-TRIHYDROXYANTHRACENE are not available. 1,8,9-TRIHYDROXYANTHRACENE is probably combustible.

Safety Profile

Questionable carcinogen withexperimental neoplastigenic and tumorigenic data.Mutation data reported. Skin contact can cause folliculitis.Absorption can cause kidney damage and intestinaldisturbances. Combustible when heated. When heated todecompositi

Purification Methods

Crystallise it from pet ether and pKEst ~dry it in vcuo.[Beilstein 6 IV 7602.]

Properties of 1,8,9-TRIHYDROXYANTHRACENE

Melting point:	181 °C
Boiling point:	327.84°C (rough estimate)
Density	1.2022 (rough estimate)
refractive index	1.5767 (estimate)
storage temp.	Sealed in dry,Room Temperature
pka	6.23±0.30(Predicted)
color	Yellow powder
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference	480-22-8(CAS DataBase Reference)
EPA Substance Registry System	1,8,9-Anthracenetriol (480-22-8)

Safety information for 1,8,9-TRIHYDROXYANTHRACENE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.