1,8,9-TRIHYDROXYANTHRACENE
- CAS NO.:480-22-8
- Empirical Formula: C14H10O3
- Molecular Weight: 226.23
- MDL number: MFCD00001250
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:52
What is 1,8,9-TRIHYDROXYANTHRACENE?
Chemical properties
yellow crystalline powder
The Uses of 1,8,9-TRIHYDROXYANTHRACENE
Antipsoriatic.
Definition
ChEBI: An anthracenetriol that is anthracene substituted by hydroxy groups at positions 1, 8 and 9.
brand name
Anthra-Derm (Dermik); DrithoCreme (Dermik); Drithoscalp (Dermik); Lasan (Stiefel).
General Description
Odorless yellow leaflets or needles; yellow powder. Tasteless. Filtrate from water suspension is neutral to litmus. When exposed to air, alkaline solutions turn red and lose their fluorescence.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
1,8,9-TRIHYDROXYANTHRACENE is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. 1,8,9-TRIHYDROXYANTHRACENE is incompatible with strong oxidizing agents. .
Fire Hazard
Flash point data for 1,8,9-TRIHYDROXYANTHRACENE are not available. 1,8,9-TRIHYDROXYANTHRACENE is probably combustible.
Safety Profile
Questionable carcinogen withexperimental neoplastigenic and tumorigenic data.Mutation data reported. Skin contact can cause folliculitis.Absorption can cause kidney damage and intestinaldisturbances. Combustible when heated. When heated todecompositi
Purification Methods
Crystallise it from pet ether and pKEst ~dry it in vcuo.[Beilstein 6 IV 7602.]
Properties of 1,8,9-TRIHYDROXYANTHRACENE
| Melting point: | 181 °C |
| Boiling point: | 327.84°C (rough estimate) |
| Density | 1.2022 (rough estimate) |
| refractive index | 1.5767 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 6.23±0.30(Predicted) |
| color | Yellow powder |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 480-22-8(CAS DataBase Reference) |
| EPA Substance Registry System | 1,8,9-Anthracenetriol (480-22-8) |
Safety information for 1,8,9-TRIHYDROXYANTHRACENE
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,8,9-TRIHYDROXYANTHRACENE
New Products
Cyclopropane-1,1-dicarboxylic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity tert-Butyl (2S)-[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate 4-amino-2-fluoro-N- methylbenzamide 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine N-Boc-1,4-butanediamine 4-Bromo-2-fluoro-N-methylbenzamide valeronitrile 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-Hydroxypropionitrile 5-azidovalericacid 6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (4-Methoxyphenyl) hydrazine HydrochlorideRelated products of tetrahydrofuran








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