1,8-Diamino-3,6-dioxaoctane

Synonym(s):1,2-Bis(2-aminoethoxy)ethane;1,8-Diamino-3,6-dioxaoctane;2,2′-(Ethylenedioxy)diethylamine

CAS NO.：929-59-9
Empirical Formula: C6H16N2O2
Molecular Weight: 148.2
MDL number: MFCD00040474
EINECS: 213-203-6
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-08 10:32:36

What is 1,8-Diamino-3,6-dioxaoctane?

Description

Amino-PEG2-Amine is a crosslinker containing two amino groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Chemical properties

CLEAR COLOURLESS LIQUID

The Uses of 1,8-Diamino-3,6-dioxaoctane

2,2'-(Ethylenedioxy)bis(ethylamine) is used to linker to form conjugates of manganese-doped zinc sulfide nanoparticles with folic acid.

What are the applications of Application

1,8-Diamino-3,6-dioxaoctane is a chelating agent that has been shown to have antibacterial efficacy against gram-positive bacteria. It has been demonstrated to bind to a variety of functionalities such as amines, low energy metals, and hydroxy groups. It has been studied in the synthesis of coordination complexes with a range of geometric structures. The synthesis methods for this compound include solid-phase synthesis and hydrolysis of ethylenediamine. This compound has also been used as an electron donor in fluorescence techniques and morphology studies.

Definition

ChEBI: Ethylene glycol bis(2-aminoethyl) ether is an ether.

Flammability and Explosibility

Not classified

Properties of 1,8-Diamino-3,6-dioxaoctane

Boiling point:	105-109 °C6 mm Hg(lit.)
Density	1.015 g/mL at 25 °C(lit.)
vapor pressure	71Pa at 20℃
refractive index	n20/D 1.461(lit.)
Flash point:	>230 °F
storage temp.	Store below +30°C.
solubility	soluble in Dimethylformamide, Methanol
pka	9.04±0.10(Predicted)
form	Liquid
color	Colorless to Almost colorless
Water Solubility	Soluble in 0.4 parts water.
Sensitive	Hygroscopic
BRN	1739187
CAS DataBase Reference	929-59-9(CAS DataBase Reference)
EPA Substance Registry System	Ethanamine, 2,2'-[1,2-ethanediylbis(oxy)]bis- (929-59-9)

Safety information for 1,8-Diamino-3,6-dioxaoctane

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin H334:Sensitisation, respiratory
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.