(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
Synonym(s):Clobetasol impurity J (PhEur);Clobetasol Related Compound A (USP)
- CAS NO.：1486466-31-2
- Empirical Formula: C25H30ClFO4
- Molecular Weight: 448.95
- MDL number: MFCD11558988
- Update Date: 2026-05-28 01:12:29
![(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Structural](https://img.chemicalbook.in/CAS/20180906/GIF/1486466-31-2.gif)
What is (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione?
The Uses of (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione, is an impurity of Clobetasol (C583490), a topical corticosteroid, and a Glucocorticoid, used as an anti-inflammatory agent.
Properties of (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
| Melting point: | >276°C (dec.) |
| Boiling point: | 563.7±50.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Dioxane (Very Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (S |
| form | neat |
| pka | 12.96±0.70(Predicted) |
| color | White to off-White |
Safety information for (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H373:Specific target organ toxicity, repeated exposure H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione manufacturer
GLP Pharma Standards
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Phone:+91-7893074638
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product: Clobetasol Propionate Related Compound A/Clobetasol Propionate - Impurity J 1486466-31-2 NLT 95%
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