1,7-Bis-boc-1,4,7-triazaheptane
- CAS NO.：117499-16-8
- Empirical Formula: C14H29N3O4
- Molecular Weight: 303.4
- MDL number: MFCD11226825
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:17:09
What is 1,7-Bis-boc-1,4,7-triazaheptane?
Description
1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE contains two Boc protecting groups which can be removed under acidic conditions. The remaining free amines can further react with carbonyl moieties.
Chemical properties
1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE is white powder
The Uses of 1,7-Bis-boc-1,4,7-triazaheptane
1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE is used in the preparation of bifunctional chelators that have been then applied to the synthesis of monoclonal antibody conjugates for tumor targeting.
in vitro
1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Properties of 1,7-Bis-boc-1,4,7-triazaheptane
| Melting point: | 68-70°C |
| Boiling point: | 440.5±30.0 °C(Predicted) |
| Density | 1.035±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 12.28±0.46(Predicted) |
| color | White to Off-White |
Safety information for 1,7-Bis-boc-1,4,7-triazaheptane
Computed Descriptors for 1,7-Bis-boc-1,4,7-triazaheptane
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