1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE
Synonym(s):1,4,7,10-Tetraazacyclododecane tetrahydrochloride
- CAS NO.：10045-25-7
- Empirical Formula: C8H21ClN4
- Molecular Weight: 208.73
- MDL number: MFCD00068484
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-31 15:04:38
What is 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE?
Chemical properties
white crystalline solid
The Uses of 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE
Cyclen tetrahydrochloride may be used for the synthesis of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methyleneethylphosphinic acid), a new macrocyclic polyaza polyphosphinate ligand. It may also be used in the synthesis of anthraquinone-pendant cyclen.
General Description
Cyclen tetrahydrochloride is a macrocycle hydrochloride salt. It can be synthesized using perhydro-2a,4a,6a,8a-tetraazacyclopenteno[1,3-f,g]acenaphthylene as a precursor. Cyclen tetrahydrochloride has an orthorhombic crystal structure. Cations are reported to exhibit crystallographic two-fold rotation symmetry and [3333] quadrangular conformation, having protonated N atoms at corner positions. Synthesis of cyclen from the corresponding butanedione-protected linear tetramines has been reported.
Properties of 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE
| Melting point: | 297-300 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Crystalline Solid |
| color | White |
| Sensitive | Hygroscopic |
| CAS DataBase Reference | 10045-25-7(CAS DataBase Reference) |
Safety information for 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H311:Acute toxicity,dermal H314:Skin corrosion/irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE
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