1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE

Synonym(s):1,4,7,10-Tetraazacyclododecane tetrahydrochloride

CAS NO.：10045-25-7
Empirical Formula: C8H21ClN4
Molecular Weight: 208.73
MDL number: MFCD00068484
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:55:45

1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE Structural

What is 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE?

Chemical properties

white crystalline solid

The Uses of 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE

Cyclen tetrahydrochloride may be used for the synthesis of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methyleneethylphosphinic acid), a new macrocyclic polyaza polyphosphinate ligand. It may also be used in the synthesis of anthraquinone-pendant cyclen.

General Description

Cyclen tetrahydrochloride is a macrocycle hydrochloride salt. It can be synthesized using perhydro-2a,4a,6a,8a-tetraazacyclopenteno[1,3-f,g]acenaphthylene as a precursor. Cyclen tetrahydrochloride has an orthorhombic crystal structure. Cations are reported to exhibit crystallographic two-fold rotation symmetry and [3333] quadrangular conformation, having protonated N atoms at corner positions. Synthesis of cyclen from the corresponding butanedione-protected linear tetramines has been reported.

Properties of 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE

Melting point:	297-300 °C
storage temp.	Inert atmosphere,Room Temperature
form	Crystalline Solid
color	White
Sensitive	Hygroscopic
CAS DataBase Reference	10045-25-7(CAS DataBase Reference)

Safety information for 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H311:Acute toxicity,dermal H314:Skin corrosion/irritation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.