1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
Synonym(s):2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride
- CAS NO.：100991-92-2
- Empirical Formula: C5H12ClNO3
- Molecular Weight: 169.61
- MDL number: MFCD03427380
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:48
What is 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE?
Description
1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.
The Uses of 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.
What are the applications of Application
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride is a glycogen phosphorylase inhibitor
General Description
1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.
Biochem/physiol Actions
Inhibitor of glycogen phosphorylase and α-glucosidases.
Properties of 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
| Melting point: | 110-112 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1)) |
| storage temp. | 2-8°C |
| solubility | DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml |
| form | A crystalline solid |
Safety information for 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
Computed Descriptors for 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
New Products
4-Iodo-3,5-dimethylbenzonitrile 2-fluoro-4-iodoaniline 2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 6,6'-methylenebis(9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one) 3-Bromo-2-fluorobenzoic acid Quinuclidine-4-carbonitrile N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzeneRelated products of tetrahydrofuran
You may like
-
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride CAS 100991-92-2View Details
100991-92-2 -
6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole 98%View Details
2115779-15-0 -
4-bromo-1H-pyrazole-3-carboxylic acid 98%View Details
13745-17-0 -
230971-72-9 (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol 98%View Details
230971-72-9 -
Isopropyl amine Hydrochloride 99%View Details
15572-56-2 -
19501-58-7 99%View Details
19501-58-7 -
Cyclopropane-1,1-dicarboxylic acid 99%View Details
598-10-7 -
230971-71-8 (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol 98%View Details
230971-71-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.