1,4-BIS(2-HYDROXYETHYL)PIPERAZINE
Synonym(s):1,4-Piperazinediethanol
- CAS NO.:122-96-3
- Empirical Formula: C8H18N2O2
- Molecular Weight: 174.24
- MDL number: MFCD00006157
- EINECS: 204-586-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:35
What is 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE?
Chemical properties
white crystalline powder
The Uses of 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE
1,4-Piperazinediethanol is useful in the synthesis of salt-inducible kinase inhibitors for the treatment of diseases.
Flammability and Explosibility
Not classified
Properties of 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE
| Melting point: | 133.5-136 °C(lit.) |
| Boiling point: | 215-220 °C50 mm Hg(lit.) |
| Density | 1.097 |
| vapor pressure | 0.004Pa at 20℃ |
| refractive index | 1.4540 (estimate) |
| Flash point: | 166℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 14.66±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Soluble in water. |
| CAS DataBase Reference | 122-96-3(CAS DataBase Reference) |
| EPA Substance Registry System | 1,4-Piperazinediethanol (122-96-3) |
Safety information for 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE
| InChIKey | VARKIGWTYBUWNT-UHFFFAOYSA-N |
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideRelated products of tetrahydrofuran


![2-PHENOXY-1-[4-(2-PHENOXY-ACETYL)-PIPERAZIN-1-YL]-ETHANONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB9768707.gif)


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