1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

Synonym(s):1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole;Togni’s Reagent

White to light yellow solid

Mild, electrophilic, hypervalent iodine CF3 reagent effective for the trifluoromethylation of a wide range of substrates.

Togni’s Reagent is used in trifluoromethylation reactions.

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole is used in trifluormethylation of a variety of compounds

Melting point:	75-79 °C
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	powder
color	white to off-white
Stability:	Moisture Sensitive

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H228:Flammable solids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

InChIKey

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