1,3-Dicyclohexylthiourea

The Uses of 1,3-Dicyclohexylthiourea

1,3-Dicyclohexylthiourea is used in the evaluation of its sensitivity, specificity and relative predictivity of battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens.

General Description

White crystals.

Air & Water Reactions

1,3-Dicyclohexylthiourea may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

1,3-Dicyclohexylthiourea is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). 1,3-Dicyclohexylthiourea is incompatible with acids and oxidizing agents. 1,3-Dicyclohexylthiourea reacts with water.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 1,3-Dicyclohexylthiourea emits very toxic fumes.

Fire Hazard

Flash point data for 1,3-Dicyclohexylthiourea are not available. 1,3-Dicyclohexylthiourea is probably combustible.