12-Hydroxydodecanoic acid
Synonym(s):12-Hydroxylauric acid
- CAS NO.：505-95-3
- Empirical Formula: C12H24O3
- Molecular Weight: 216.32
- MDL number: MFCD00002739
- EINECS: 208-025-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:54:56
What is 12-Hydroxydodecanoic acid?
Chemical properties
white to off-white powder
The Uses of 12-Hydroxydodecanoic acid
12-Hydroxydodecanoic acid was used in the synthesis of high molecular weight poly[(12-hydroxydodecanoate)-co-(12-hydroxystearate)] [poly(12HD-co-12HS)] samples with variable monomer ratios using methyl 12-hydroxystearate.
The Uses of 12-Hydroxydodecanoic acid
12-Hydroxylauric Acid is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum.
Definition
ChEBI: 12-hydroxylauric acid is a medium-chain fatty acid that is the 12-hydroxylated derivative of lauric acid. It has a role as a human metabolite. It is functionally related to a dodecanoic acid. It is a conjugate acid of a 12-hydroxylaurate.
Purification Methods
Crystallise the acid from toluene [Sadowik et al. J Am Chem Soc 108 7789 1986]. [Beilstein 3 III 658.]
Properties of 12-Hydroxydodecanoic acid
| Melting point: | 85-88 °C(lit.) |
| Boiling point: | 296.74°C (rough estimate) |
| Density | 0.988±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.4410 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.78±0.10(Predicted) |
| color | White |
| BRN | 1238370 |
| Stability: | Stable. Incompatible with bases, reducing agents and oxidizing agents. Combustible. May cause dust explosion when mixed with air. |
Safety information for 12-Hydroxydodecanoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 12-Hydroxydodecanoic acid
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