1,2-Diphenylethylenediamine
Synonym(s):trans-1,2-Diphenylethylene;trans-1,2-Diphenylethylene;trans-Stilbene
- CAS NO.：16635-95-3
- Empirical Formula: C14H16N2
- Molecular Weight: 212.29
- MDL number: MFCD00064300
- EINECS: 605-438-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-12 17:28:22
What is 1,2-Diphenylethylenediamine?
The Uses of 1,2-Diphenylethylenediamine
1,2-Diphenylethylenediamine (DPE) has been found to react in a neutral medium with catecholamines and other catechol compounds in the presence of hexacyanoferrate(III) to give a compound that fluoresces intensely. The reaction is accelerated by amino acids such as glycine. Nohta et al. described a sensitive spectrofluorimetric method for determining catecholamines with 1,2diphenylethylenediamine. The method is based on the reaction of catechol compounds in a neutral medium with 1,2-diphenylethylenediamine in the presence of hexacyanoferrate(II1) and glycine at ambient temperature. The fluorescence shows excitation and emission maxima around 345 and 480 nm, respectively. The method is simple, selective for catechol compounds, and very sensitive. Catecholamines can be determined at concentrations as low as 15-20 pmol ml-1[1].
References
[1] H. Nohta, Y. Ohkura, A. Mitsui. “Spectrofluorimetric determination of catecholamines with 1,2-diphenylethylenediamine.” Analytica Chimica Acta 165 1 (1984): 171–176.
Properties of 1,2-Diphenylethylenediamine
| Melting point: | 123-125 °C(lit.) |
| Boiling point: | 305-307 °C744 mm Hg(lit.) |
| Density | 0.97 g/mL at 25 °C(lit.) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | soluble in Methanol |
| pka | 9.78±0.10(Predicted) |
| form | powder to crystal |
| color | White to Yellow to Orange |
| CAS DataBase Reference | 16635-95-3(CAS DataBase Reference) |
Safety information for 1,2-Diphenylethylenediamine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 1,2-Diphenylethylenediamine
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