1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
- CAS NO.：17082-61-0
- Empirical Formula: C10H22O2Si2
- Molecular Weight: 230.45
- MDL number: MFCD00010798
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:03
What is 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE?
Chemical properties
clear colorless liquid
The Uses of 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
1,2-Bis(trimethylsilyloxy)cyclobutene is a useful chemical reactant used in the preparation and biological activity of serine and threonine β-lactones as inhibitors of hepatitis A virus 3C cysteine proteinase.
General Description
Photocycloaddition of 2-cyclohexenones to 1,2-bis(trimethyl-siloxy)cyclobutene has been studied. It undergoes Aldol condensation reaction with carbonyl compounds. It reacts with Br2 to give cyclobutanedione.
Properties of 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
| Boiling point: | 58-59 °C2 mm Hg(lit.) |
| Density | 0.897 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 142 °F |
| storage temp. | Inert atmosphere,2-8°C |
| form | clear liquid |
| Specific Gravity | 0.87 |
| color | Colorless to Light yellow |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 1367530 |
| CAS DataBase Reference | 17082-61-0(CAS DataBase Reference) |
Safety information for 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
| InChIKey | WOBRFSDEZREQAB-UHFFFAOYSA-N |
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