1,2-Bis(maleimido)ethane

Chemical properties

Off White Solid

The Uses of 1,2-Bis(maleimido)ethane

A short, sulfhydryl reactive homobifunctional crosslinking reagent

The Uses of 1,2-Bis(maleimido)ethane

A short, sulfhydryl reactive homobifunctional crosslinking reagent.

The Uses of 1,2-Bis(maleimido)ethane

1,2-Bis(maleimido)ethane is a protein cross-linking agent.

What are the applications of Application

Ethylene-bis-maleimide is a homobifunctional sulfhydryl-reactive crosslinker

General Description

BMOE, BMB and BMH are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. Because BMOE, BMB and BMH have the same reactivity but differ in length, the relative success of these three reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.