10-Hydroxycamptothecin
Synonym(s):10-Hydroxycamptothecin, HCPT;Camptothecin, 10-Hydroxy-, Camptotheca acuminata - CAS 64439-81-2 - Calbiochem
- CAS NO.:64439-81-2
- Empirical Formula: C20H16N2O5
- Molecular Weight: 364.35
- MDL number: MFCD00274425
- EINECS: 613-598-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is 10-Hydroxycamptothecin?
Chemical properties
mp 268-270°C loss on drying <1%
The Uses of 10-Hydroxycamptothecin
Topoisomerase inhibitor
The Uses of 10-Hydroxycamptothecin
therapeutic effects for liver cancer, stomach, and neck cancer and leukemia.
Properties of 10-Hydroxycamptothecin
| Melting point: | 230-237°C |
| Boiling point: | 820.7±65.0 °C(Predicted) |
| Density | 1.60 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: ≥ 37.5 mg/mL (102.92 mM) |
| pka | 8.93±0.40(Predicted) |
| form | Pale yellow powder |
| color | Yellow |
| CAS DataBase Reference | 64439-81-2(CAS DataBase Reference) |
Safety information for 10-Hydroxycamptothecin
| Signal word | Danger |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H340:Germ cell mutagenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. |
Computed Descriptors for 10-Hydroxycamptothecin
| InChIKey | LCZZWLIDINBPRC-FQEVSTJZSA-N |
New Products
Cyclopropane-1,1-dicarboxylic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity tert-Butyl (2S)-[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate 4-amino-2-fluoro-N- methylbenzamide 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine N-Boc-1,4-butanediamine 4-Bromo-2-fluoro-N-methylbenzamide valeronitrile 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-Hydroxypropionitrile 5-azidovalericacid 6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (4-Methoxyphenyl) hydrazine HydrochlorideRelated products of tetrahydrofuran





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