10-Hydroxycamptothecin
Synonym(s):10-Hydroxycamptothecin, HCPT;Camptothecin, 10-Hydroxy-, Camptotheca acuminata - CAS 64439-81-2 - Calbiochem
- CAS NO.：64439-81-2
- Empirical Formula: C20H16N2O5
- Molecular Weight: 364.35
- MDL number: MFCD00274425
- EINECS: 613-598-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-08-20 20:20:01
What is 10-Hydroxycamptothecin?
Chemical properties
mp 268-270°C loss on drying <1%
The Uses of 10-Hydroxycamptothecin
Topoisomerase inhibitor
The Uses of 10-Hydroxycamptothecin
therapeutic effects for liver cancer, stomach, and neck cancer and leukemia.
Properties of 10-Hydroxycamptothecin
| Melting point: | 230-237°C |
| Boiling point: | 820.7±65.0 °C(Predicted) |
| Density | 1.60 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: ≥ 37.5 mg/mL (102.92 mM) |
| pka | 8.93±0.40(Predicted) |
| form | Pale yellow powder |
| color | Yellow |
| CAS DataBase Reference | 64439-81-2(CAS DataBase Reference) |
Safety information for 10-Hydroxycamptothecin
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H340:Germ cell mutagenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. |
Computed Descriptors for 10-Hydroxycamptothecin
| InChIKey | LCZZWLIDINBPRC-FQEVSTJZSA-N |
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![9-HYDROXYCAMPTOTHECIN, [12-3H(N)]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB5680508.gif)
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