1-PYRENEBUTYRIC ACID

Synonym(s):4-(1-Pyrenyl)butyric acid;4-(1-Pyrenyl)-butyric acid;PyBA

CAS NO.：3443-45-6
Empirical Formula: C20H16O2
Molecular Weight: 288.34
MDL number: MFCD00004141
EINECS: 222-354-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:12:55

What is 1-PYRENEBUTYRIC ACID?

Chemical properties

Pale yellow or yellow-beige crystalline powder

The Uses of 1-PYRENEBUTYRIC ACID

1-Pyrenebutyric Acid is a fluorescent probe used to study proteins, lipids, nucleic acids and other biological systems. The fluorescence lifetime of 1-Pyrenebutyric Acid depends on local oxygen and fr ee radical concentration.

The Uses of 1-PYRENEBUTYRIC ACID

General Description

1-Pyrenebutyric acid (PBA) is a conjugated polymer that has a large π system and a carboxylic group. It is majorly used in surface functionalization. It has a high fluorescence efficiency and stability that make it useful in optoelectronic applications.

Purification Methods

Crystallise the butyric acid from *benzene, EtOH, EtOH/water (7:3 v/v) or *C6H6/AcOH. Dry it over P2O5. [Chu & Thomas J Am Chem Soc 108 6270 1986, Beilstein 9 IV 2731.]

Properties of 1-PYRENEBUTYRIC ACID

Melting point:	184-186 °C (lit.)
Boiling point:	370.57°C (rough estimate)
Density	1.1742 (rough estimate)
refractive index	1.4800 (estimate)
storage temp.	Store below +30°C.
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
pka	4.76±0.10(Predicted)
form	Crystalline Powder
color	Pale yellow or yellow-beige
Water Solubility	Partially soluble in water.
BRN	2140554
CAS DataBase Reference	3443-45-6(CAS DataBase Reference)
EPA Substance Registry System	1-Pyrenebutanoic acid (3443-45-6)

Safety information for 1-PYRENEBUTYRIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.