1-Piperidinepropanol
Synonym(s):1-(3-Hydroxypropyl)piperidine
- CAS NO.：104-58-5
- Empirical Formula: C8H17NO
- Molecular Weight: 143.23
- MDL number: MFCD00023781
- EINECS: 203-216-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:12:59
What is 1-Piperidinepropanol?
The Uses of 1-Piperidinepropanol
1-Piperidinepropanol is used in preparation of Ionizable Amine lipids for lipid Nanoparticle compounds that deliver Nucleic Acids.
The Uses of 1-Piperidinepropanol
Reactant in: Mitsunobu reaction of intramolecular nitrile oxide-alkene cycloadditions1 Suzuki-coupling2Reactant for synthesis of: Histamine H3 receptor antagonists3 Protein lysine methyltransferase G9a inhibitors4 Serotonin-4 receptors antagonists5 Checkpoint kinase Chk2 inhibitors6
What are the applications of Application
1-Piperidinepropanol is used to prepare isothiourea and was a reactant in Mitsunobu reaction of intramolecular nitrile oxide-alkene cycloadditions
Properties of 1-Piperidinepropanol
| Boiling point: | 94-95 °C/0.5 mmHg (lit.) |
| Density | 0.944 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 208 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | liquid |
| pka | 15.12±0.10(Predicted) |
| color | Colourless to light yellow |
| CAS DataBase Reference | 104-58-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Piperidinepropanol(104-58-5) |
Safety information for 1-Piperidinepropanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Piperidinepropanol
| InChIKey | PLRXAFVBCHEMGD-UHFFFAOYSA-N |
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