1-(PHENYLSULFONYL)INDOLE
Synonym(s):1-(Benzenesulfonyl)indole;Benzenesulfonic acid indolide;NSC 237040;NSC 683530
- CAS NO.:40899-71-6
- Empirical Formula: C14H11NO2S
- Molecular Weight: 257.31
- MDL number: MFCD00134318
- EINECS: 642-614-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:52:09
What is 1-(PHENYLSULFONYL)INDOLE?
Chemical properties
Off-white to pink crystalline powder
The Uses of 1-(PHENYLSULFONYL)INDOLE
Reactant for preparation of:
- Antiplasmodial agents
- Antifungal agents
- Anti HIV-1 agents
- Agonists of the histamine H4 receptor
- Antibacterial agents
- Camalexin analogs
- CDK inhibitors and cytotoxic agents
- Histone Deacetylase inhibitors
Definition
ChEBI: 1-(benzenesulfonyl)indole is a sulfonamide.
Synthesis Reference(s)
Synthesis, p. 136, 1979
Tetrahedron Letters, 29, p. 2151, 1988 DOI: 10.1016/S0040-4039(00)86696-4
Properties of 1-(PHENYLSULFONYL)INDOLE
| Melting point: | 78-80 °C(lit.) |
| Boiling point: | 192°C 3mm |
| Density | 1.26±0.1 g/cm3(Predicted) |
| Flash point: | 192°C/3mm |
| storage temp. | Sealed in dry,Room Temperature |
| BRN | 1286712 |
| CAS DataBase Reference | 40899-71-6(CAS DataBase Reference) |
Safety information for 1-(PHENYLSULFONYL)INDOLE
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 1-(PHENYLSULFONYL)INDOLE
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran

![5-({1-[(4-METHYLPHENYL)SULFONYL]-1H-INDOL-3-YL}METHYLENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB2326726.gif)
![4-(2-(1-[(4-METHOXYPHENYL)SULFONYL]-1H-INDOL-3-YL)ETHYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB0189743.gif)

![1-[(4-METHYLPHENYL)SULFONYL]-1H-INDOL-5-AMINIUM CHLORIDE](https://img.chemicalbook.in/CAS/GIF/306937-24-6.gif)

![N-(4-FLUOROBENZYL)-2-[2-((1-[(4-METHYLPHENYL)SULFONYL]-1H-INDOL-4-YL)OXY)ETHOXY]-1-ETHANAMINE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB0738619.gif)

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