1-(Pentafluoropropionyl)imidazole
Synonym(s):1-(Perfluoropropionyl)imidazole;PFPI
- CAS NO.：71735-32-5
- Empirical Formula: C6H3F5N2O
- Molecular Weight: 214.09
- MDL number: MFCD00014502
- EINECS: 275-944-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:55:43
What is 1-(Pentafluoropropionyl)imidazole?
The Uses of 1-(Pentafluoropropionyl)imidazole
PFPI may be used to incubate the lyophilized samples, for derivatization during GC/MS analysis to measure total d-chiro-Inositol content absorbed by rodents.
What are the applications of Application
1-(Pentafluoropropionyl)imidazole is A derivatization agent for alcohols and carboxylic acids in the GC
General Description
Derivatization before a GC analysis helps in yielding distinctive products, which can be achieved using a derivatizing reagent that reacts with amino and hydroxyl functionalities quantitatively. 1-(Pentafluoropropionyl)imidazole (PFPI) is a derivatizing reagent which was found to give high yield of products than pentafluoropropionic anhydride during preparation of methyl ester/pentafluoropropionyl derivatives.
Properties of 1-(Pentafluoropropionyl)imidazole
| Boiling point: | 46-47°C 15mm |
| Density | 1.4 g/mL at 20 °C(lit.) |
| refractive index | n |
| storage temp. | −20°C |
| pka | 1.81±0.10(Predicted) |
| Sensitive | Hygroscopic |
| CAS DataBase Reference | 71735-32-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1-(2,2,3,3,3-Pentafluoro-1-oxopropyl)-1H-imidazole (71735-32-5) |
Safety information for 1-(Pentafluoropropionyl)imidazole
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(Pentafluoropropionyl)imidazole
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