1-(PENTAFLUOROPROPIONYL)IMIDAZOLE
Synonym(s):1-(Perfluoropropionyl)imidazole;PFPI
- CAS NO.：71735-32-5
- Empirical Formula: C6H3F5N2O
- Molecular Weight: 214.09
- MDL number: MFCD00014502
- EINECS: 275-944-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:37
What is 1-(PENTAFLUOROPROPIONYL)IMIDAZOLE?
The Uses of 1-(PENTAFLUOROPROPIONYL)IMIDAZOLE
PFPI may be used to incubate the lyophilized samples, for derivatization during GC/MS analysis to measure total d-chiro-Inositol content absorbed by rodents.
What are the applications of Application
1-(Pentafluoropropionyl)imidazole is A derivatization agent for alcohols and carboxylic acids in the GC
General Description
Derivatization before a GC analysis helps in yielding distinctive products, which can be achieved using a derivatizing reagent that reacts with amino and hydroxyl functionalities quantitatively. 1-(Pentafluoropropionyl)imidazole (PFPI) is a derivatizing reagent which was found to give high yield of products than pentafluoropropionic anhydride during preparation of methyl ester/pentafluoropropionyl derivatives.
Properties of 1-(PENTAFLUOROPROPIONYL)IMIDAZOLE
| Boiling point: | 46-47°C 15mm |
| Density | 1.4 g/mL at 20 °C(lit.) |
| refractive index | n |
| storage temp. | −20°C |
| pka | 1.81±0.10(Predicted) |
| Sensitive | Hygroscopic |
| CAS DataBase Reference | 71735-32-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1-(2,2,3,3,3-Pentafluoro-1-oxopropyl)-1H-imidazole (71735-32-5) |
Safety information for 1-(PENTAFLUOROPROPIONYL)IMIDAZOLE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(PENTAFLUOROPROPIONYL)IMIDAZOLE
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
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