1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
Synonym(s):1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
- Empirical Formula: C27H16F5O4P
- Molecular Weight: 530.379317
- MDL number: MFCD09265125
What is 1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate?
The Uses of 1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
- Staudinger ligation reagent for the conjugation of amine and azide containing compounds or biomolecules.
- The amine functionalized molecule first reacts with the phosphine through the activated pentafluorophenyl ester.The azide-molecule is then reacted with the newly labeled phosphine to form the iminophosphorane, and the aza-ylide is subsequently captured by the methyl ester to yield the covalent conjugated product.
The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method
What are the applications of Application
2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester is a Staudinger ligation reagent for the conjugation of amine and azide containing compounds or biomolecules
Properties of 1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
| Melting point: | 109-111 °C |
| storage temp. | -20°C |
Safety information for 1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
Computed Descriptors for 1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
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