1-METHYL-3-INDOLEACETIC ACID
Synonym(s):2-(N-Methylindole-3-yl)acetic acid;NSC 78007
- CAS NO.：1912-48-7
- Empirical Formula: C11H11NO2
- Molecular Weight: 189.21
- MDL number: MFCD00130160
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:21
What is 1-METHYL-3-INDOLEACETIC ACID?
Chemical properties
Light Brown Solid
The Uses of 1-METHYL-3-INDOLEACETIC ACID
1-Methylindole-3-acetic Acid is a N-methylated derivative of Indole-3-acetic acid, a natural auxin, with plant growth regulating activity.
The Uses of 1-METHYL-3-INDOLEACETIC ACID
- Reactant for enantioselective preparation of α-aryl alkylcarboxylic acids
- Reactant for preparation of PKC inhibitor methylindolylpyridinylmethylpiperidinylindolylpyrroledione for protein kinase C imaging
- Reactant for stereoselective preparation of δ-lactones via Michael addition/lactonization with unsaturated carboxylates
- Reactant for stereoselective preparation of vindorosine, vindoline, and analogs
- Reactant for preparation of (indolyl)pyrrol-2-ones as VEGF-R inhibitors, antiangiogenic agents, and protein kinase inhibitors
- Reactant for synthesis of 3-aryl-5-alkyl-2,5-dihydrofuran-2-ones and their carbanalogues as antifungal agents
What are the applications of Application
1-Methyl-3-indoleacetic acid is an important precursor to PKC inhibitor methylindolypyridinylmet
General Description
1-Methyl-3-indoleacetic acid is an indole derivative. Direct and riboflavin- or Rose-Bengal-sensitized photo-oxidation of 1-methyl-3-indoleacetic acid in aqueous buffer (pH 5 or pH 8) containing 10% methanol has been studied.
Properties of 1-METHYL-3-INDOLEACETIC ACID
| Melting point: | 126-128 °C (lit.) |
| Boiling point: | 392.0±17.0 °C(Predicted) |
| Density | 1.20±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform, Methanol |
| pka | 4.53±0.30(Predicted) |
| form | Crystalline Powder |
| color | White to tan |
Safety information for 1-METHYL-3-INDOLEACETIC ACID
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-METHYL-3-INDOLEACETIC ACID
New Products
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![METHYL 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)ACETATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB9217720.gif)
![1-(P-CHLORBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID [2-14C]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2769912.gif)
![2-[1-(6-CHLORO-3-PYRIDAZINYL)-1H-INDOL-3-YL]ACETIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB4476946.gif)
![METHYL 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-3-(4-METHOXYANILINO)ACRYLATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB7118300.gif)
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