1,1,1-Trifluoro-4-iodobutane

CAS NO.：461-17-6
Empirical Formula: C4H6F3I
Molecular Weight: 237.99
MDL number: MFCD00041543
SAFETY DATA SHEET (SDS)
Update Date: 2025-08-08 17:45:00

What is 1,1,1-Trifluoro-4-iodobutane?

Description

1,1,1-Trifluoro-4-iodobutane is an organic compound with the chemical formula CIF3. It is a colorless liquid that reacts with water and alcohol to form hydrogen fluoride and hydrofluoric acid. 1,1,1-Trifluoro-4-iodobutane is a potent sensitizer that can irritate the skin and eyes. It has been used experimentally as a solvent for diethyl ether in the synthesis of piperidinium salts. The cavity viscosity of 1,1,1-trifluoro-4-iodobutane has been measured at room temperature and found to be 0.0038 Pa·s at 25 °C. In laboratory tests, this molecule has shown antibacterial activity against Propionibacterium acnes (P. acnes) and Staphylococcus aureus (S. aureus).

The Uses of 1,1,1-Trifluoro-4-iodobutane

1,1,1-Trifluoro-4-Iodobutane can be used to prepare small molecule inhibitors of SLC15A4 possessing anti-inflammatory activity.

Properties of 1,1,1-Trifluoro-4-iodobutane

Boiling point:	126 °C
Density	1.85
refractive index	1.4326
Flash point:	>100°C
storage temp.	2-8°C(protect from light)
form	clear liquid
color	Colorless to Light yellow to Light orange
Sensitive	Light Sensitive
BRN	1736064
InChI	InChI=1S/C4H6F3I/c5-4(6,7)2-1-3-8/h1-3H2
CAS DataBase Reference	461-17-6(CAS DataBase Reference)

Safety information for 1,1,1-Trifluoro-4-iodobutane

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.