1-(ETHOXYCARBONYLMETHYL)PIPERAZINE
Synonym(s):N-(Carboethoxymethyl)-piperazine;1-(Ethoxycarbonylmethyl)piperazine;Ethyl 1-piperazineacetate
- CAS NO.：40004-08-8
- Empirical Formula: C8H16N2O2
- Molecular Weight: 172.22
- MDL number: MFCD00040739
- EINECS: 254-745-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:27:08
What is 1-(ETHOXYCARBONYLMETHYL)PIPERAZINE?
Chemical properties
1-(ETHOXYCARBONYLMETHYL)PIPERAZINE is Clear Thick Oil
The Uses of 1-(ETHOXYCARBONYLMETHYL)PIPERAZINE
1-(ETHOXYCARBONYLMETHYL)PIPERAZINE is used in the preparation of aralkylpiperazine- and aryl-substituted hydrazines, particularly benzylpiperazineacetyl hydrazones of hydroxyaryl aldehydes, as selecti ve inducers of apoptosis and activators of procaspases for use as anticancer agents.
The Uses of 1-(ETHOXYCARBONYLMETHYL)PIPERAZINE
N-(Ethoxycarbonylmethyl)piperazine is used in the preparation of aralkylpiperazine- and aryl-substituted hydrazines, particularly benzylpiperazineacetyl hydrazones of hydroxyaryl aldehydes, as selective inducers of apoptosis and activators of procaspases for use as anticancer agents.
Definition
ChEBI: Ethyl piperazinoacetate is an alpha-amino acid ester.
Properties of 1-(ETHOXYCARBONYLMETHYL)PIPERAZINE
| Boiling point: | 127°C 13mm |
| Density | 1.048 g/mL at 20 °C (lit.) |
| refractive index | n |
| Flash point: | 127°C/13mm |
| storage temp. | -20°C |
| solubility | Chloroform, Methanol |
| form | Oil |
| pka | 8.96±0.10(Predicted) |
| color | Clear |
| Water Solubility | Soluble in water, chloroform, and methanol. |
| Sensitive | Air Sensitive |
| BRN | 743260 |
| CAS DataBase Reference | 40004-08-8(CAS DataBase Reference) |
Safety information for 1-(ETHOXYCARBONYLMETHYL)PIPERAZINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(ETHOXYCARBONYLMETHYL)PIPERAZINE
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![ETHYL 2-[4-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERAZINO]PROPANOATE](https://img.chemicalbook.in/CAS/GIF/260555-47-3.gif)
![ETHYL 2-(4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]PIPERAZINO)ACETATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB6254487.gif)
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