1-(DIETHOXYMETHYL)IMIDAZOLE
- CAS NO.：61278-81-7
- Empirical Formula: C8H14N2O2
- Molecular Weight: 170.21
- MDL number: MFCD00956331
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:38
What is 1-(DIETHOXYMETHYL)IMIDAZOLE?
The Uses of 1-(DIETHOXYMETHYL)IMIDAZOLE
1-(Diethoxymethyl)imidazole may be used in the preparation of various hydroxy- and amino-functionalized imidazoles, via isoprene-mediated lithiation followed by reaction with an electrophile.
General Description
1-(Diethoxymethyl)imidazole is an orthoamide protected imidazole. The dianion reacts selectively at the 2 position 1-(Diethoxymethyl)imidazole is a 1-substituted imidazoles. Isoprene-mediated lithiation of 1-(diethoxymethyl)imidazole, leads to the preparation of the corresponding 2-lithio intermediate, which reacts with different electrophiles to afford 2-functionalised imidazoles.
Properties of 1-(DIETHOXYMETHYL)IMIDAZOLE
| Boiling point: | 52 °C(Press: 0.02 Torr) |
| Density | 1.041 g/mL at 20 °C (lit.) |
| refractive index | n |
| Flash point: | 112℃ |
| storage temp. | 2-8°C |
| pka | 6.13±0.20(Predicted) |
| BRN | 908482 |
Safety information for 1-(DIETHOXYMETHYL)IMIDAZOLE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(DIETHOXYMETHYL)IMIDAZOLE
1-(DIETHOXYMETHYL)IMIDAZOLE manufacturer
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