1-Chloroadamantane

Chemical properties

white to light grey adhering crystalline solid or

The Uses of 1-Chloroadamantane

1-Chloroadamantane, an adamantane derivative shown to exhibit virucidal activity against the Newcastle disease virus in chick embryo fibroblasts. (Adamantane EP Impurity A)

The Uses of 1-Chloroadamantane

1-Chloroadamantane was employed as precursor for the synthesis of perfluoroadmantane derivatives via aerosol direct fluorination.

Synthesis Reference(s)

Synthetic Communications, 19, p. 1697, 1989 DOI: 10.1080/00397918908051068

General Description

An unusual zwitterionic diradical intermediate complex was generated during the photoinduced electron-transfer substitution reaction between 1-chloroadamantane and tert-butylamine system in a hydrocarbon glass.

Purification Methods

Crystallise the chloride from aqueous MeOH and sublime it at 100o/12torr. It also crystallises from MeOH at -70o. [Stetter et al. Chem Ber 92 1629 1959, Schleyer & Nicholas J Am Chem Soc 83 2700 1961, Beilstein 5 IV 469.]