1-Chloro-2-propanol
Synonym(s):Chloropropanol;Propylene chlorohydrin
- CAS NO.：127-00-4
- Empirical Formula: C3H7ClO
- Molecular Weight: 94.54
- MDL number: MFCD00004530
- EINECS: 204-819-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:16
What is 1-Chloro-2-propanol?
Chemical properties
colourless to light yellow liquid
The Uses of 1-Chloro-2-propanol
1-Chloro-2-propanol has been used as:
- chemical intermediate for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol
- as α,β-halohydrin standard during the enzymatic synthesis of α,β-halohydrins from gaseous alkenes
What are the applications of Application
1-Chloro-2-propanol is a chlorinated propanol used in chemical synthesis
Definition
ChEBI: 1-chloropropan-2-ol is a secondary alcohol that is isopropanol in which one of the methyl hydrogen atoms is substituted by chlorine. It is an organochlorine compound and a secondary alcohol. It derives from a hydride of a propane.
General Description
Clear colorless to light amber liquid with a mild non residual odor.
Air & Water Reactions
Soluble in water.
Reactivity Profile
May be sensitive to prolonged exposure to light. Incompatible with strong oxidizing agents.
Fire Hazard
1-Chloro-2-propanol is combustible.
Properties of 1-Chloro-2-propanol
| Boiling point: | 126-127 °C(lit.) |
| Density | 1.111 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 125 °F |
| storage temp. | Flammables area |
| Water Solubility | Soluble in water |
| solubility | Chloroform (Soluble), Methanol (Slightly) |
| form | clear liquid |
| pka | 14.09±0.20(Predicted) |
| color | Colorless to Light yellow |
| Merck | 14,7851 |
| BRN | 773653 |
| Exposure limits | ACGIH: TWA 1 ppm (Skin) |
| Stability: | Stable. Flammable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 127-00-4(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Chloro-2-propanol (127-00-4) |
Safety information for 1-Chloro-2-propanol
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Chloro-2-propanol
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