1-CBZ-2-PIPERIDINECARBOXYLIC ACID
- CAS NO.：28697-07-6
- Empirical Formula: C14H17NO4
- Molecular Weight: 263.29
- MDL number: MFCD01863568
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-08 17:45:00
What is 1-CBZ-2-PIPERIDINECARBOXYLIC ACID?
Chemical properties
White solid
The Uses of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
1,?2-?Piperidinedicarboxyl?ic Acid 1-?(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-?[(R)?-?2-?methylpyrrolidin-?2-?yl]?-?1H-?benzimidazole-?4-?carboxamide (ABT-?888) as the Poly(ADP-?ribose) Polymerase (PARP) inhibitor for the treatment of cancer.
Properties of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
| Melting point: | 110 °C(Solv: ethanol (64-17-5)) |
| Boiling point: | 443.9±45.0 °C(Predicted) |
| Density | 1.265±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | powder to crystal |
| pka | 4.01±0.20(Predicted) |
| color | White to Almost white |
Safety information for 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
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![1-[(4-NITROBENZYLOXY)CARBONYL]-PIPERIDINE-2-CARBOXYLIC ACID](https://img.chemicalbook.in/CAS/GIF/193269-76-0.gif)
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