4-Bromo-1,2-difluorobenzene
- CAS NO.：348-61-8
- Empirical Formula: C6H3BrF2
- Molecular Weight: 192.99
- MDL number: MFCD00000304
- EINECS: 206-481-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:07
What is 4-Bromo-1,2-difluorobenzene?
Chemical properties
clear colorless to pale yellow liquid
The Uses of 4-Bromo-1,2-difluorobenzene
Intermediates of Liquid Crystals
The Uses of 4-Bromo-1,2-difluorobenzene
4-Bromo-1,2-difluorobenzene has been used in the preparation of 4-benzyl-2-(3,4-difluorophenyl)-2-hydroxy-morpholine.
General Description
Regioselective nucleophilic aromatic substitution reaction of 4-bromo-1,2-difluorobenzene with benzyl alcohol has been investigated.
Properties of 4-Bromo-1,2-difluorobenzene
| Melting point: | -4 °C |
| Boiling point: | 150-151 °C(lit.) |
| Density | 1.707 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 92 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | Liquid |
| Specific Gravity | 1.707 |
| color | Clear colorless to pale yellow |
| Water Solubility | insoluble |
| BRN | 1934811 |
| CAS DataBase Reference | 348-61-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Bromo-3,4-difluorobenzene(348-61-8) |
Safety information for 4-Bromo-1,2-difluorobenzene
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
Computed Descriptors for 4-Bromo-1,2-difluorobenzene
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