1,2-Difluorobenzene
- CAS NO.：367-11-3
- Empirical Formula: C6H4F2
- Molecular Weight: 114.09
- MDL number: MFCD00000284
- EINECS: 206-680-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:05
What is 1,2-Difluorobenzene?
Chemical properties
colourless liquid
The Uses of 1,2-Difluorobenzene
1,2-Difluorobenzene is used in electrochemical analysis of transition metal complexes. 1,2-difluorobenzene is also a potent inhibitor of NMDA receptor.
The Uses of 1,2-Difluorobenzene
1,2-Difluorobenzene(1,2-DFB) has been used to study the mechanism of dissociation of o-, m- and p-difluorobenzene ions by threshold photoelectron photoion coincidence spectroscopy. It has been used to study the room temperature adsorption of 1,2-DFB, 1,2-dichlorobenzene and 1,2-dibromobenzene on Si(100)2x1 by X-ray photoelectron spectroscopy and temperature programmed desorption. It is used as solvent in electrochemical studies on transition metal complexes. It is also applied as a solvent useful for electrochemical studies on transition metal complexes.
Definition
ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 2.
General Description
1,2-Difluorobenzene undergoes defluorination under very mild conditions by H2 in the presence of NaOAc over rhodium pyridylphosphine and bipyridyl complexes tethered on a silica-supported palladium catalyst.
Properties of 1,2-Difluorobenzene
| Melting point: | −34 °C(lit.) |
| Boiling point: | 92 °C(lit.) |
| Density | 1.158 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 36 °F |
| storage temp. | Flammables area |
| solubility | Chloroform, Methanol |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 1.158 |
| Water Solubility | Not miscible or difficult to mix in water. |
| BRN | 1905113 |
| Dielectric constant | 14.26 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Highly flammable. Note low flash point. |
| CAS DataBase Reference | 367-11-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1,2-difluoro-(367-11-3) |
| EPA Substance Registry System | Benzene, 1,2-difluoro- (367-11-3) |
Safety information for 1,2-Difluorobenzene
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H225:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. |
Computed Descriptors for 1,2-Difluorobenzene
1,2-Difluorobenzene manufacturer
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