1-Boc-4-(aminomethyl)piperidine
Synonym(s):N-(tert-Butoxycarbonyl)-4-aminomethylpiperidine;1,1-Dimethylethyl 4-(aminomethyl)-1-piperidinecarboxylate
- CAS NO.：144222-22-0
- Empirical Formula: C11H22N2O2
- Molecular Weight: 214.3
- MDL number: MFCD01076207
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:24
What is 1-Boc-4-(aminomethyl)piperidine?
Chemical properties
White Low Melting Solid
The Uses of 1-Boc-4-(aminomethyl)piperidine
1-Boc-4-(aminomethyl)piperidine is a protected 4-substituted piperidinecarboxylate used in the preparation of orally active platelet-activating factor antagonists as well as other biologically active compounds.
The Uses of 1-Boc-4-(aminomethyl)piperidine
1-Boc-4-(aminomethyl)piperidine is used in the preparation biologically active compounds and orally active platelet-activating factor antagonists. It is used as an inhibitor for Kinesin spindle protein. It is an active reactant involved in the enantioselective synthesis of N-alkyl terminal aziridines.Precursor in the preparation of a variety of different protein agonists or antagonists including: Orphan G-protein coupled receptor GPR119 agonist with antidiabetic potential, Pim-1 inhibitors, and Aspartic acid protease inhibitors.
Properties of 1-Boc-4-(aminomethyl)piperidine
| Boiling point: | 237-238 °C(lit.) |
| Density | 1.013 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in chloroform and methanol. |
| pka | 10.13±0.29(Predicted) |
| form | Liquid or Low Melting Solid |
| color | Colorless to yellow |
| InChI | InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3 |
| CAS DataBase Reference | 144222-22-0(CAS DataBase Reference) |
Safety information for 1-Boc-4-(aminomethyl)piperidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 1-Boc-4-(aminomethyl)piperidine
| InChIKey | KLKBCNDBOVRQIJ-UHFFFAOYSA-N |
| SMILES | N1(C(OC(C)(C)C)=O)CCC(CN)CC1 |
1-Boc-4-(aminomethyl)piperidine manufacturer
BTC Pharmaceuticals Technology India
Andhra Pradesh
product: 1-boc-4-aminomethyl Piperidine, Cas No: 144222-22-0
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