1-Benzyl-4-hydroxypiperidine
Synonym(s):1-Benzyl-4-piperidinol
- CAS NO.：4727-72-4
- Empirical Formula: C12H17NO
- Molecular Weight: 191.27
- MDL number: MFCD00006503
- EINECS: 225-226-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-04 16:42:01
What is 1-Benzyl-4-hydroxypiperidine?
Chemical properties
WHITE TO YELLOWISH CRYSTALLINE POWDER
The Uses of 1-Benzyl-4-hydroxypiperidine
1-Benzyl-4-hydroxypiperidine is the reactant for synthesis of: Muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist1 Fatty acid amide hydrolase inhibitors PI3 kinase-alpha inhibitors Flavonoid derivatives used as dual binding acetylcholinesterase inhibitors Urotensin-II receptor antagonists Rho kinase inhibitors.
The Uses of 1-Benzyl-4-hydroxypiperidine
A piperidine based pesticide
The Uses of 1-Benzyl-4-hydroxypiperidine
1-Benzyl-4-hydroxypiperidine was used as an alternative molecule to study the ligand concentration attached to the epoxy-activated Sepharose 6B.
Synthesis Reference(s)
Journal of the American Chemical Society, 108, p. 3512, 1986 DOI: 10.1021/ja00272a059
Properties of 1-Benzyl-4-hydroxypiperidine
| Melting point: | 61-63 °C(lit.) |
| Boiling point: | 127-128 °C2 mm Hg(lit.) |
| Density | 1.0096 (rough estimate) |
| refractive index | 1.5212 (estimate) |
| Flash point: | 121-123°C/0.7mm |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform, Methanol |
| pka | 14.87±0.20(Predicted) |
| form | Crystalline Powder |
| color | White to yellow |
| Sensitive | Hygroscopic |
| BRN | 146118 |
| CAS DataBase Reference | 4727-72-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Piperidinol, 1-(phenylmethyl)-(4727-72-4) |
Safety information for 1-Benzyl-4-hydroxypiperidine
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Benzyl-4-hydroxypiperidine
1-Benzyl-4-hydroxypiperidine manufacturer
JSK Chemicals
2Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 4727-72-4 1-Benzyl-4-hydroxypiperidine, 95% 99%
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 1-Benzylpiperidin-4-ol
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