1-Adamantyl isocyanate
- CAS NO.：4411-25-0
- Empirical Formula: C11H15NO
- Molecular Weight: 177.24
- MDL number: MFCD00134405
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:49:12
What is 1-Adamantyl isocyanate?
Chemical properties
White powder
The Uses of 1-Adamantyl isocyanate
1-Adamantyl isocyanate may be used in the preparation of:
- adamantyl-functionalized nanoparticles, via thiol-isocyanate reaction of thiol-modified nanoparticles1 4-[3-(aryl or -cycloalkyl)ureido]butyryl compound
- 4-(3-adamantan-1-yl-ureido)butyric acid, via reaction with 4-aminobutanoic acid in DMF
- 4-(3-adamantan-1-yl-ureido)butyryloxy compound
- 12-(3-adamantan-1-yl-ureido) dodecanoic acid (AUDA)
- adamantyl-phenylsulfonamide ureas
- 1-adamantan-1-yl-3-(hydroxyalkyl)ureas, via reaction with with hydroxyalkylamines
Synthesis Reference(s)
The Journal of Organic Chemistry, 55, p. 4282, 1990 DOI: 10.1021/jo00301a014
General Description
1-Adamantyl isocyanate is an isocyanate derivative.
Purification Methods
Recrystallise the isocyanate from n-hexane and sublime it. Irritant. [Stetter & Wulff Chem Ber 95 2302 1962.]
Properties of 1-Adamantyl isocyanate
| Melting point: | 144-146 °C (lit.) |
| Boiling point: | 309.18°C (rough estimate) |
| Density | 1.0290 (rough estimate) |
| refractive index | 1.5302 (estimate) |
| solubility | soluble in Acetone |
| form | Powder |
| color | White |
| CAS DataBase Reference | 4411-25-0(CAS DataBase Reference) |
Safety information for 1-Adamantyl isocyanate
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Adamantyl isocyanate
New Products
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