1-(4-Fluorophenyl)piperazine
- CAS NO.：2252-63-3
- Empirical Formula: C10H13FN2
- Molecular Weight: 180.22
- MDL number: MFCD00005960
- EINECS: 218-846-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:28
What is 1-(4-Fluorophenyl)piperazine?
Chemical properties
clear yellowish liquid after melting
The Uses of 1-(4-Fluorophenyl)piperazine
1-(4-Fluorophenyl)piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidatio n.
The Uses of 1-(4-Fluorophenyl)piperazine
1-(4-Fluorophenyl)piperazine was used in the synthesis of N,N-disubstituted piperazine. It is a major metabolite of niaparazine, a sedative, a hypnotic drug.
Properties of 1-(4-Fluorophenyl)piperazine
| Melting point: | 30-33 °C (lit.) |
| Boiling point: | 118-123 °C/0.1 mmHg (lit.) |
| Density | 1.0 |
| refractive index | 1.5585-1.5605 |
| Flash point: | >230 °F |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | 8.93±0.10(Predicted) |
| form | Liquid After Melting |
| color | Clear yellow |
| Water Solubility | Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 610723 |
| CAS DataBase Reference | 2252-63-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-(P-fluorophenyl)piperazine(2252-63-3) |
Safety information for 1-(4-Fluorophenyl)piperazine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(4-Fluorophenyl)piperazine
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
![2-[4-(4-FLUOROPHENYL)PIPERAZINO]QUINOXALINE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB4668314.gif)
![N-(4-[4-(4-FLUOROPHENYL)PIPERAZINO]PHENYL)PENTANAMIDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB7232707.gif)
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