1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
Synonym(s):1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride;3′-Hydroxyphenyl-2-methylaminoacetophenone hydrochloride;Phenylephrone hydrochloride
- CAS NO.：94240-17-2
- Empirical Formula: C9H12ClNO2
- Molecular Weight: 201.65
- MDL number: MFCD01727458
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:50:26
What is 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride?
Chemical properties
Green Solid
The Uses of 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
Impurity C of Phenylephrine.
The Uses of 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
Phenylephrine Hydrochloride (Phenylephrine EP Impurity C; Phenylephrine USP Related Compound C (1-(3-Hydroxyphenyl)-2-(methylamino)ethan-1-one Hydrochloride)) is an impurity C of Phenylephrine.
Preparation
Preparation by conversion of the base with 35% ethanolic hydrogen chloride.
Properties of 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
| Melting point: | 231-233°C |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Beige |
Safety information for 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
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