1-(3-Chlorophenyl)piperazine hydrochloride
Synonym(s):m-CPP;1-(3-Chlorophenyl)piperazine ammonium salt
- CAS NO.：65369-76-8
- Empirical Formula: C10H14Cl2N2
- Molecular Weight: 233.14
- MDL number: MFCD00039032
- EINECS: 265-718-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:38:03
What is 1-(3-Chlorophenyl)piperazine hydrochloride?
Chemical properties
Off-white solid
The Uses of 1-(3-Chlorophenyl)piperazine hydrochloride
Chlorophenyl Piperazine Hydrochloride Salt is a useful intermediate for organic synthesis and other chemical properties. Trazodone impurity.
General Description
1-(3-Chlorophenyl)-piperazine, also known as meta-chlorophenylpiperazine or mCPP, is a designer drug analog of aryl-substituted piperazines. A stimulant, serotonin antagonist and reuptake inhibitor (SARU), mCPP can also be detected as a primary urinary metabolite of the antidepressant drug trazadone. This certified solution standard is suitable for use in piperazine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.
Biological Activity
5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo .
Properties of 1-(3-Chlorophenyl)piperazine hydrochloride
| Melting point: | 210-214 °C (dec.)(lit.) |
| Density | 1,193g/cm |
| refractive index | 1,598-1,600 |
| Flash point: | 9℃ |
| storage temp. | Store at RT |
| solubility | methanol: soluble |
| form | Solid |
| color | Pale brown |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 65369-76-8(CAS DataBase Reference) |
Safety information for 1-(3-Chlorophenyl)piperazine hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(3-Chlorophenyl)piperazine hydrochloride
1-(3-Chlorophenyl)piperazine hydrochloride manufacturer
SVR DRUGS AND INTERMEDIATES
New Products
Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione TRIFLOURO ACETICACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
65369-76-8 1-(3-Chloro Phenyl) Piperazine Hydrochloride 99%View Details
65369-76-8 -
65369-76-8 98%View Details
65369-76-8 -
1-(3-Chlorophenyl)piperazine hydrochloride 99%View Details
65369-76-8 -
1-(3-Chlorophenyl)-piperazine hydrochloride 98%View Details -
65369-76-8 1-(3-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 95-99%View Details
65369-76-8 -
1-(3-Chlorophenyl)piperazine hydrochloride CAS 65369-76-8View Details
65369-76-8 -
65369-76-8 1-(3-Chlorophenyl)piperazine hydrochloride 99.20%View Details
65369-76-8 -
1-(3- Chlorophenyl) Piperazine HydrochlorideView Details
119532-26-2